With the cost to sequence genomes declining dramatically, scientists and researchers are applying next generation sequencing (NGS) technology to new discoveries and clinical research applications at a rapidly  expanding rate. These applications are driving the need for sample preparation  workflows that prepare the DNA/RNA libraries prior to sequencing. This growing appetite for new kits plus the demand for higher-throughput solutions often mean that start-up to sequencing can take months. For the laboratory manager and user, the challenge is not installing and starting to use the  automated sample preparation system, it is the difficult and time-consuming steps to get the automated methods to create the proper libraries that are required for sequencing and the generation of high-quality genomic data.